MORPHINE ENHANCES THE ACTIVITY OF THERMORECEPTIVE COLD-SPECIFIC LAMINA-I SPINOTHALAMIC NEURONS IN THE CAT

被引:57
作者
CRAIG, AD [1 ]
HUNSLEY, SJ [1 ]
机构
[1] BARROW NEUROL INST, DIV NEUROSURG, PHOENIX, AZ 85013 USA
关键词
THERMORECEPTION; THERMOREGULATION; PAIN; ANALGESIA; SPINAL PHYSIOLOGY; OPIATE;
D O I
10.1016/0006-8993(91)90719-C
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The possibility that morphine might differentially affect spinal neurons responsive to small-diameter thermoreceptive-specific afferents was tested. Systemic morphine enhanced a portion or all of the stimulus-response function of 7 of 9 lamina I spinothalamic tract cells specifically sensitive to cold applied to the glabrous hindpaw in the cat. This result contrasts strongly with the predominant inhibition of nociceptive lamina I neurons by morphine.
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页码:93 / 97
页数:5
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