Follow-up of children born with an umbilical arterial blood pH<7

被引:46
作者
Nagel, HTC
Vandenbussche, FPHA
Oepkes, D
JennekensSchinkel, A
Laan, LAEM
Gravenhorst, JB
机构
[1] UNIV LEIDEN HOSP,DEPT NEUROL,DIV NEUROPSYCHOL,2300 RC LEIDEN,NETHERLANDS
[2] UNIV LEIDEN HOSP,DEPT NEUROL,DIV PEDIAT NEUROL,2300 RC LEIDEN,NETHERLANDS
关键词
perinatal asphyxia; umbilical arterial blood pH; psychomotor development; Denver Developmental Screening Test;
D O I
10.1016/0002-9378(95)90423-9
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: We performed neurodevelopmental assessment in children born with an umbilical artery pH <7. STUDY DESIGN: All infants born with an umbilical artery pH <7 from a 19-month period were retrieved from the obstetric database. Obstetric, neonatal, and pediatric records were reviewed. At an age of 1 to 3 years, children were visited at home for semi-structured questioning of the mother and a Denver Developmental Screening Test of the child. RESULTS: During the study period 1614 umbilical artery pH measurements were entered in the database. Thirty (1.9%) were <7. From this group 23 infants were admitted to the neonatal intensive care unit, and 8 of them required intubation. Twenty-eight children survived the neonatal period. Three children experienced an episode of mild hypertonia. One child had a mild motor developmental delay. CONCLUSION: Babies born with an umbilical artery pH <7 are at great risk to experience considerable short-term morbidity. Those who leave the neonatal intensive care unit without major problems have good outcomes, and pessimism in counseling their parents is unwarranted.
引用
收藏
页码:1758 / 1764
页数:7
相关论文
共 26 条
[1]   ACID-BASE STATUS AT BIRTH AND NEURODEVELOPMENTAL OUTCOME AT 4-1/2 YEARS [J].
DENNIS, J ;
JOHNSON, A ;
MUTCH, L ;
YUDKIN, P ;
JOHNSON, P .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1989, 161 (01) :213-220
[2]   APGAR SCORE, MECONIUM AND ACIDEMIA AT BIRTH IN RELATION TO NEONATAL NEUROLOGICAL MORBIDITY IN TERM INFANTS [J].
DIJXHOORN, MJ ;
VISSER, GHA ;
FIDLER, VJ ;
TOUWEN, BCL ;
HUISJES, HJ .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1986, 93 (03) :217-222
[3]   THE RELATION BETWEEN UMBILICAL PH VALUES AND NEONATAL NEUROLOGICAL MORBIDITY IN FULL TERM APPROPRIATE-FOR-DATES INFANTS [J].
DIJXHOORN, MJ ;
VISSER, GHA ;
HUISJES, HJ ;
FIDLER, V ;
TOUWEN, BCL .
EARLY HUMAN DEVELOPMENT, 1985, 11 (01) :33-42
[4]   PERCENTILES FOR GAS VALUES IN HUMAN UMBILICAL-CORD BLOOD [J].
ESKES, TKAB ;
JONGSMA, HW ;
HOUX, PCW .
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1983, 14 (05) :341-346
[5]   SEVERE ACIDOSIS AND SUBSEQUENT NEUROLOGIC STATUS [J].
FEE, SC ;
MALEE, K ;
DEDDISH, R ;
MINOGUE, JP ;
SOCOL, ML .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1990, 162 (03) :802-806
[6]  
GOLDABER KG, 1991, OBSTET GYNECOL, V78, P1103
[7]  
GOODWIN TM, 1992, AM J OBSTET GYNECOL, V162, P1506
[8]   ARTERIAL OR VENOUS UMBILICAL PH AS A MEASURE OF NEONATAL MORBIDITY [J].
HUISJES, HJ ;
AARNOUDSE, JG .
EARLY HUMAN DEVELOPMENT, 1979, 3 (02) :155-161
[9]  
KUBLI F, 1972, RESPIRATORY GAS EXCH, P487
[10]   MOTOR AND COGNITIVE DEFICITS AFTER INTRAPARTUM ASPHYXIA IN THE MATURE FETUS [J].
LOW, JA ;
GALBRAITH, RS ;
MUIR, DW ;
KILLEN, HL ;
PATER, EA ;
KARCHMAR, EJ .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1988, 158 (02) :356-361