AGE-SPECIFIC PREVALENCE OF ANTIBODY TO ENTEROTOXIGENIC ESCHERICHIA-COLI IN ECUADORIAN AND GERMAN CHILDREN

被引：22

作者：

BRUSSOW, H ^{[1
]}

SIDOTI, J ^{[1
]}

LINK, H ^{[1
]}

HOANG, YK ^{[1
]}

BARCLAY, D ^{[1
]}

DIRREN, H ^{[1
]}

FREIRE, WB ^{[1
]}

机构：

[1] CONSEJO NACL DESARROLLO, QUITO, ECUADOR

来源：

JOURNAL OF INFECTIOUS DISEASES | 1990年 / 162卷 / 04期

关键词：

D O I：

10.1093/infdis/162.4.974

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Serum samples from 1397 Ecuadorian children 0–5 years of age were tested by ELISA for antibodies to enterotoxigenic Escherichia coli (ETEC). A gradual prevalence and titer increase was seen for IgG antibodies to heat-labile enterotoxin in children 6–18 months old; 90% prevalences were reached in the second year of life. At this age <10% of West German children showed IgG antibodies to heat-labile enterotoxin. In Ecuador age-related ETEC-specific antibody titer increases correlated with age-related prevalence of diarrheal disease. On the other hand, pooled lipopolysaccharide from different ETEC-associated 0 serogroups could not be used as a seroepidemiologic marker of ETEC infections. © 1990, by The University of Chicago.

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页码：974 / 977

页数：4

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