ORAL-CANCER DEVELOPMENT IN PATIENTS WITH ORAL LICHEN-PLANUS

被引：127

作者：

BARNARD, NA

SCULLY, C

EVESON, JW

CUNNINGHAM, S

PORTER, SR

机构：

[1] Centre for the Study of Oral Disease, University Department of Oral Medicine, Pathology and Microbiology, Bristol Dental Hospital and School

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1993年 / 22卷 / 09期

关键词：

CANCER; LICHEN PLANUS; MOUTH DISEASES; PREMALIGNANT LESIONS;

D O I：

10.1111/j.1600-0714.1993.tb00134.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

There has been considerable controversy as to whether oral lichen planus (LP) has a premalignant potential. This study retrospectively examined the records of 241 British patients with histologically confirmed LP seen during the 10-year period 1982-92. Nine patients (3.7%) were known to have developed well-differentiated invasive carcinoma or carcinoma in situ in an area of LP. Most carcinomas at presentation were in areas of atrophic and/or erosive LP, 6 were in patients older than 65 years, and 6 were on the tongue. The results support a small but clinically important premalignant potential for LP.

引用

页码：421 / 424

页数：4

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