NITROIMIDAZOLES AS ANAEROBIC ELECTRON-ACCEPTORS FOR XANTHINE-OXIDASE

被引：59

作者：

CLARKE, ED

GOULDING, KH

WARDMAN, P

机构：

[1] MT VERNON HOSP,CANC RES CAMPAIGN,GRAY LAB,NORTHWOOD HA6 2RN,MIDDX,ENGLAND

[2] HATFIELD POLYTECH,SCH NAT SCI,HATFIELD AL10 9AB,HERTS,ENGLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1982年 / 31卷 / 20期

关键词：

D O I：

10.1016/0006-2952(82)90556-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3237 / 3242

页数：6

共 27 条

[1] STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE DEVELOPMENT OF HYPOXIC CELL RADIOSENSITIZERS .1. SENSITIZATION EFFICIENCY [J].

ADAMS, GE ;

CLARKE, ED ;

FLOCKHART, IR ;

JACOBS, RS ;

SEHMI, DS ;

STRATFORD, IJ ;

WARDMAN, P ;

WATTS, ME ;

PARRICK, J ;

WALLACE, RG ;

SMITHEN, CE .

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1979, 35 (02) :133-150

[2] ELECTRON-AFFINIC SENSITIZATION .7. CORRELATION BETWEEN STRUCTURES ONE-ELECTRON REDUCTION POTENTIALS, AND EFFICIENCIES OF NITROIMIDAZOLES AS HYPOXIC CELL RADIOSENSITIZERS [J].

ADAMS, GE ;

FLOCKHART, IR ;

SMITHEN, CE ;

STRATFORD, IJ ;

WARDMAN, P ;

WATTS, ME .

RADIATION RESEARCH, 1976, 67 (01) :9-20

[3]

ADAMS GE, 1978, BR J CANCER S3, V37

[4]

BRADY LW, 1980, RAD SENSITIZERS THEI

[5]

BRECCIA A, 1982, ADV TOPICS HYPOXIC C

[6]

BRECCIA A, 1979, RADIOSENSITIZERS HYP

[7]

CHRYSTAL EJT, 1980, MOL PHARMACOL, V18, P105

[8] ANAEROBIC REDUCTION OF NITROIMIDAZOLES BY REDUCED FLAVIN MONO-NUCLEOTIDE AND BY XANTHINE-OXIDASE [J].

CLARKE, ED ;

WARDMAN, P ;

GOULDING, KH .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (19) :2684-2687

[9]

GILLETTE JR, 1971, HDB EXPT PHARMACOL 2, P349

[10]

Hansch C, 1979, SUBSTITUENT CONSTANT

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