MALIGNANT-MELANOMA OF THE VULVA - A CLINICOPATHOLOGICAL STUDY OF 50 WOMEN

被引：73

作者：

BRADGATE, MG ^{[1
]}

ROLLASON, TP ^{[1
]}

MCCONKEY, CC ^{[1
]}

POWELL, J ^{[1
]}

机构：

[1] BIRMINGHAM & MIDLAND HOSP WOMEN, DEPT PATHOL, BIRMINGHAM B11 4HL, W MIDLANDS, ENGLAND

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1990年 / 97卷 / 02期

关键词：

D O I：

10.1111/j.1471-0528.1990.tb01737.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Summary. A clinicopathological review of 50 primary malignant melanomas of the vulva in the West Midlands region of England is presented. The overall 5‐year‐survival rate was 35%, when adjusted for age. Significant predictors of survival were clinical stage, patient age, tumour ulceration, cell type and mitotic rate. Tumour thickness was of prognostic importance but as a prognostic variable it did not operate independently of stage and as most lesions were deeply invasive at presentation vulval tumours must be separated for prognostic purposes into bands at greater overall thicknesses than those used for skin melanomas generally. There was no significant relation between survival and type of surgery performed as a primary therapeutic procedure. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：124 / 133

页数：10

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