ACYL CARRIER PROTEIN - EFFECTS OF ACETYLATION AND TRYPTIC HYDROLYSIS ON FUNCTION IN FATTY ACID SYNTHESIS

被引：35

作者：

MAJERUS, PW

机构：

[1] Departments of Biological Chemistry and Internal Medicine, Washington University, School of Medicine, St. Louis

来源：

SCIENCE | 1968年 / 159卷 / 3813期

关键词：

D O I：

10.1126/science.159.3813.428

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Acetylation of the four lysine residues and the amino group of the terminal serine residue of Escherichia coli acyl carrier protein has no effect on the ability of this protein to function in fatty acid synthesis. Subsequent trypsin hydrolysis resulting in complete inactivation cleaves a single arginyl peptide bond, releasing the amino terminal hexapeptide from the molecule.

引用

页码：428 / &