HUMAN PROTO-ONCOGENE C-MOS MAPS TO 8Q11

被引：61

作者：

CAUBET, JF ^{[1
]}

MATHIEUMAHUL, D ^{[1
]}

BERNHEIM, A ^{[1
]}

LARSEN, CJ ^{[1
]}

BERGER, R ^{[1
]}

机构：

[1] HOP ST LOUIS, UER HEMATOL,ONCOL & IMMUNOHEMATOL LAB,CNRS,LP 101, 2 PL DR FOURNIER, F-75475 PARIS 10, FRANCE

来源：

EMBO JOURNAL | 1985年 / 4卷 / 09期

关键词：

D O I：

10.1002/j.1460-2075.1985.tb03921.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hybridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos have been found in acute leukemia with the chromosomal translocation t(8;21)(q22;q22).

引用

页码：2245 / 2248

页数：4

共 15 条

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