BINDING OF HEAT-SHOCK PROTEIN-70 (HSP70) TO TUBULIN

被引：55

作者：

SANCHEZ, C

PADILLA, R

PACIUCCI, R

ZABALA, JC

AVILA, J

机构：

[1] UNIV AUTONOMA MADRID,FAC CIENCIAS,CSIC,CTR BIOL MOLEC SEVERO OCHOA,E-28049 MADRID,SPAIN

[2] UNIV CANTABRIA,FAC MED,DEPT MOLEC BIOL,E-39005 SANTANDER,SPAIN

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1994年 / 310卷 / 02期

关键词：

D O I：

10.1006/abbi.1994.1188

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Binding of heat-shock protein (hsp70) to polymerized tubulin has been investigated by in vitro experiments. The tubulin region involved in binding to hsp70 corresponds to the carboxy-terminal residues 431-444, also involved in the association with other microtubule-associated proteins (MAPs). Additionally, the putative tubulin binding motif in the hsp70 protein contains a sequence related to the motif described for MAP1B protein. (C) 1994 Academic Press, Inc.

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页码：428 / 432

页数：5

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