CUCURBITANES AND CUCURBITANE-TYPE GLYCOSIDES FROM IBERVILLEA-SONORAE

被引：24

作者：

ACHENBACH, H ^{[1
]}

HORN, K ^{[1
]}

DOMINGUEZ, XA ^{[1
]}

ROMBOLD, C ^{[1
]}

LOPEZ, EGG ^{[1
]}

机构：

[1] ITESM,DEPT QUIM,MONTERREY,NUEVO LEON,MEXICO

来源：

PHYTOCHEMISTRY | 1993年 / 33卷 / 02期

关键词：

IBERVILLEA-SONORAE (FORMERLY MAXIMOWICZIA-SONORAE); CUCURBITACEAE; ROOT (TUBER); CUCURBITACINS KINOIN-A AND KINOIN-B; KINOIN-A AND KINOIN-B GLYCOSIDES; HEXANORCUCURBITACIN KINOIN C [3-ALPHA,16-ALPHA-DIHYDROXY-4,4,9,14-TETRAMETHYL-(9-BETA,10-ALPHA)-19-NORPREGN-5-ENE-11,20-DIONE;

D O I：

10.1016/0031-9422(93)85535-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cucurbitane-type glycosides were isolated from tuber extracts of Ibervillea sonorae as the major components. Among the minor constituents the corresponding aglycones kinoin A and kinoin B and the tetramethylated 19-norpregnenedione kinoin C have been found. These compounds represent new natural products and the 2,3,6-trihydroxy-6-methyl-4-heptenyl-2 side chain at C- 1 7 of three of these compounds is unprecedented among the known cucurbitanes as well as sterols. The structures were determined by spectroscopic methods in combination with chemical degradations and modifications. Among others, 22-epi-dihydrokinoin A was prepared. The NMR data of the 22-epimers differ characteristically and allow the establishment of the relative configurations of the vicinal hydroxyl groups at C-20 and C-22 in this series of compounds.

引用

页码：437 / 445

页数：9

共 24 条

[1] FEVICORDIN-A AND FEVICORDIN-A GLUCOSIDE, NOVEL NORCUCURBITACINS FROM FEVILLEA-CORDIFOLIA [J].