USE OF NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE AS TREATMENT OF CHILDHOOD OBSTRUCTIVE SLEEP-APNEA

被引:176
作者
MARCUS, CL
WARD, SLD
MALLORY, GB
ROSEN, CL
BECKERMAN, RC
WEESEMAYER, DE
BROUILLETTE, RT
TRANG, HT
BROOKS, LJ
机构
[1] JOHNS HOPKINS UNIV, BALTIMORE, MD USA
[2] CHILDRENS HOSP LOS ANGELES, LOS ANGELES, CA 90027 USA
[3] ST LOUIS CHILDRENS HOSP, ST LOUIS, MO 63178 USA
[4] YALE UNIV, SCH MED, NEW HAVEN, CT USA
[5] TULANE UNIV, MED CTR, NEW ORLEANS, LA USA
[6] RUSH UNIV, RUSH PRESBYTERIAN ST LUKES MED CTR, CHICAGO, IL 60612 USA
[7] MCGILL UNIV, MONTREAL, PQ, CANADA
[8] HOP ANTOINE BECLERE, CLAMART, FRANCE
[9] RAINBOW BABIES & CHILDRENS HOSP, CLEVELAND, OH 44106 USA
关键词
D O I
10.1016/S0022-3476(95)70262-8
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: To determine the safety and efficacy of nasal continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA) during childhood and the effects of growth and maturation on CRAP requirements. Design: Retrospective study with use of a written questionnaire administered to pediatric practitioners treating sleep disorders. Setting: Nine academic pediatric sleep disorders centers. Results: Data were obtained for 94 patients, Three percent of patients receiving CRAP were less than 1 year, 29% were 1 to 5 years, 36% were 6 to 12 years, and 32% were 13 to 19 years of age; 64% were boys. The longest duration of CPAP use was 4 years. Indications for CRAP included OSA associated with obesity (27%), craniofacial anomalies (25%), idiopathic OSA persisting after adenoidectomy and tonsillectomy (17%), and trisomy 21 (13%), Continuous positive airway pressure was effective in 81 patients (86%), in one patient ii was unsuccessful, and in 12 patients compliance was inadequate. The median pressure required was 8 cm H2O (range, 4 to 20 cm H2O); pressure requirements were independent of age or diagnosis, Twenty-two percent of patients eventually required a modification of CPAP levels. Complications of CPAP were minor. Sixty-four percent of centers reported difficulty in obtaining funding for CRAP. Conclusions: Continuous positive airway pressure is safe, effective, and well tolerated by children and adolescents with OSA. Experience in infants is limited, As pressure requirements change with patient growth, we recommend that CPAP requirements be regularly reevaluated over time, The marked center-to-center variability in CPAP use suggests that specific indications for this therapy require clarification.
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页码:88 / 94
页数:7
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