LUTEAL FUNCTION ASSOCIATED WITH SINGLE, MULTIPLE AND ECTOPIC EMBRYO IMPLANTATION IN NATURAL CYCLES OR AFTER OVARIAN HYPERSTIMULATION FOR INVITRO FERTILIZATION GAMETE INTRAFALLOPIAN TRANSFER

被引:8
作者
WANG, L [1 ]
WARNES, GM [1 ]
KIRBY, CA [1 ]
MATTHEWS, CD [1 ]
NORMAN, RJ [1 ]
机构
[1] UNIV ADELAIDE,DEPT OBSTET & GYNAECOL,REPROD MED UNIT,ADELAIDE,SA 5001,AUSTRALIA
关键词
GIFT; IVF; Luteal function; Multiple ectopic; heterotopic pregnancy; Natural; Single;
D O I
10.1093/oxfordjournals.humrep.a137127
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Levels of reproductive steroids and gonadotrophins were analysed retrospectively during the peri-implantation period following non-conceptional and conceptional natural cycles and in cycles associated with ovarian hyperstirnulation for in-vitro fertilization or gamete intra-Fallopian transfer. In cycles not associated with conception, the luteal phase of hyperstimulated cycles (n = 100) was characterized by higher serum progesterone and oestradiol levels (P < 0.01) and with an earlier decline in steroids than in natural cycles (n = 21). On day 11 (day of oocyte recovery = day 0), the level of progesterone in twin (n = 59) and triplet (n = 13) pregnancies was higher than singleton pregnancies (n = 176) (P < 0.006, P < 0.006 respectively) while those destined to abort (n = 66) had lower progesterone levels (P < 0.01). Ectopic implantation (n = 11) had the lowest progesterone concentrations on day 11 (P < 0.01) and this may imply a delay in corpus luteum rescue or a later implantation time than intrauterine conception. © 1990 Oxford University Press.
引用
收藏
页码:476 / 480
页数:5
相关论文
共 18 条
[1]  
Batzer F.R., Hormonal evaluation of early pregnancy, Fertil Steril, 34, 1, pp. 1-13, (1980)
[2]  
Braunstein G.D., Grodin J.M., Vaitukatis J., Ross G.T., Secretory rates of human chorionic gonadotrophin by normal trophoblast, Am. J. Obstet. Gynecol, 115, pp. 447-450, (1973)
[3]  
Catt K.J., Dufau M.L., Vaitukaitis J.L., Appearance of hCG in pregnancy plasma following initiation of implantation of blastocyst, J. Clin. Endocrinol. Metab, 40, pp. 537-540, (1975)
[4]  
Confino E., Demir R.H., Friberg J., Gleicher N., The predictive value of beta HCG subunit levels in pregnancies achieved by in vitro fertilization and embryo transfer, An International Collaborative Study, 45, pp. 526-531, (1986)
[5]  
Deutinger J., Neumark J., Reinthaller A.H., Riss P., Muller-Tyl E., Fischl F., Bieglmayer C., Janisch D., Pregnancy specific parameters in early pregnancies after in vitro fertilization: Prediction of course of pregnancy, Fertil. Steril, 46, pp. 77-80, (1986)
[6]  
Dor J., Rudak E., Rotmench S., Levran D., Blankstein J., Lusky A., Nebel L., Serr D.M., Mashiach S., The role of early postimplantation beta HCG levels in the outcome of pregnancies following in-vitro fertilization, Hum. Reprod, 3, pp. 663-667, (1988)
[7]  
Huang K.E., Muechler E.K., Schwarz K.R., Goggin M., Graham M.C., Serum progesterone levels in women treatedwith human menopausal gonadotropin and human chorionic gonadotropin for in vitro fertilization, Fertil. Steril, 46, pp. 903-906, (1986)
[8]  
Johansson E.D.B., Plasma levels of progesterone in pregnancy measured by rapid competitive protein binding technique, Acta Endocrinol, 61, pp. 607-617, (1969)
[9]  
Kerin J.F., Warnes G.M., Quinn P., Kirby C.A., Jeffrey R., Matthews C.D., Seamark R.F., Cox L.W., In vitro fertilization and embryo transfer program, The University of Adelaide, J. In Vitro, 1, pp. 63-71, (1984)
[10]  
Lenton E.A., Woodward A.J., The endocrinology of conception cycles and implantation in women, J. Reprod, 36, pp. 1-15, (1988)