GENE AMPLIFICATION OF C-MYC AND N-MYC IN SMALL CELL-CARCINOMA OF THE LUNG

被引：279

作者：

WONG, AJ

RUPPERT, JM

EGGLESTON, J

HAMILTON, SR

BAYLIN, SB

VOGELSTEIN, B

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,CTR ONCOL,BALTIMORE,MD 21205

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PATHOL,BALTIMORE,MD 21205

[3] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,BALTIMORE,MD 21205

来源：

SCIENCE | 1986年 / 233卷 / 4762期

关键词：

D O I：

10.1126/science.3014659

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：461 / 464

页数：4

共 52 条

[1]

ADCOCK MW, 1984, J BIOL CHEM, V259, P3471

[2] TRANSFORMING RAS GENES FROM HUMAN-MELANOMA - A MANIFESTATION OF TUMOR HETEROGENEITY [J].

ALBINO, AP ;

LESTRANGE, R ;

OLIFF, AI ;

FURTH, ME ;

OLD, LJ .

NATURE, 1984, 308 (5954) :69-72

[3] HOMOGENEOUSLY STAINING CHROMOSOMAL REGIONS CONTAIN AMPLIFIED COPIES OF AN ABUNDANTLY EXPRESSED CELLULAR ONCOGENE (C-MYC) IN MALIGNANT NEUROENDOCRINE CELLS FROM A HUMAN-COLON CARCINOMA [J].

ALITALO, K ;

SCHWAB, M ;

LIN, CC ;

VARMUS, HE ;

BISHOP, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (06) :1707-1711

[4]

ALITALO K, 1984, MED BIOL, V62, P304

[5] PATTERNS OF THE EARLY, GROSS CHROMOSOMAL CHANGES IN MALIGNANT HUMAN GLIOMAS [J].

BIGNER, SH ;

MARK, J ;

MAHALEY, MS ;

BIGNER, DD .

HEREDITAS, 1984, 101 (01) :103-113

[6] VIRAL ONCOGENES [J].

BISHOP, JM .

CELL, 1985, 42 (01) :23-38

[7] AMPLIFICATION OF N-MYC IN UNTREATED HUMAN NEUROBLASTOMAS CORRELATES WITH ADVANCED DISEASE STAGE [J].

BRODEUR, GM ;

SEEGER, RC ;

SCHWAB, M ;

VARMUS, HE ;

BISHOP, JM .

SCIENCE, 1984, 224 (4653) :1121-1124

[8] GENE AMPLIFICATION IN HUMAN NEUROBLASTOMAS - BASIC MECHANISMS AND CLINICAL IMPLICATIONS [J].

BRODEUR, GM ;

SEEGER, RC .

CANCER GENETICS AND CYTOGENETICS, 1986, 19 (1-2) :101-111

[9] AMPLIFICATION OF ENDOGENOUS MYC-RELATED DNA-SEQUENCES IN A HUMAN MYELOID-LEUKEMIA CELL-LINE [J].

COLLINS, S ;

GROUDINE, M .

NATURE, 1982, 298 (5875) :679-681

[10]

DALLAFAVERA R, 1982, NATURE, V299, P61

← 1 2 3 4 5 6 →