MODELING OF WATER TRANSPORT AND SOLUTE RELEASE IN PHYSIOLOGICALLY SENSITIVE GELS

被引：38

作者：

HARIHARAN, D ^{[1
]}

PEPPAS, NA ^{[1
]}

机构：

[1] PURDUE UNIV,SCH CHEM ENGN,W LAFAYETTE,IN 47907

来源：

JOURNAL OF CONTROLLED RELEASE | 1993年 / 23卷 / 02期

关键词：

IONIC NETWORKS; GELS; MODELING OF DIFFUSION; SWELLING;

D O I：

10.1016/0168-3659(93)90038-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Water transport into and solute release from ionic, hydrophilic, initially glassy polymeric networks were investigated by deriving a model which takes in consideration the strong concentration dependence of the penetrant and solute diffusion coefficients. The model was solved with appropriate boundary conditions in an ionic buffered solution exhibiting simultaneous ionization of its components. Water uptake and solute release were described in terms of the Swelling Interface number and other parameters of the polymer/buffer system.

引用

页码：123 / 135

页数：13

共 24 条

[1]

Davidson G. W. R., 1986, J CONTROL RELEASE, V3, P243, DOI DOI 10.1016/0168-3659(86)90096-9

[2] THE KINETICS OF CHEMICALLY-INDUCED NONEQUILIBRIUM SWELLING OF ARTICULAR-CARTILAGE AND CORNEAL STROMA [J].