INVOLVEMENT OF 9P IN METASTATIC OVARIAN ADENOCARCINOMAS

被引:22
作者
BELLO, MJ [1 ]
MORENO, S [1 ]
REY, JA [1 ]
机构
[1] HOSP VIRGEN CAMINO,DEPT GENET,PAMPLONA,SPAIN
关键词
D O I
10.1016/0165-4608(90)90086-P
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
By a direct method and after in vitro culture, we cytogenetically analyzed five ovarian adenocarcinomas, using six samples of ascitic fluid. The structural aberrations included rearrangements of chromosomes 1 and 3, in agreement with the results of other researchers. The long arm of chromosome 6 was rearranged in three samples, but no translocation t(6;14) was found. Rearrangements involving 9p were present in all cases, with breakpoints at p13 or p22-23. © 1990.
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页码:223 / 229
页数:7
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