MITOGEN AND STRESS-RESPONSE PATHWAYS - MAP KINASE CASCADES AND PHOSPHATASE REGULATION IN MAMMALS AND YEAST

被引：527

作者：

WASKIEWICZ, AJ ^{[1
]}

COOPER, JA ^{[1
]}

机构：

[1] UNIV WASHINGTON,SEATTLE,WA 98195

来源：

CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 06期

关键词：

D O I：

10.1016/0955-0674(95)80063-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Evolutionarily conserved from yeast to man, mitogen-activated protein kinase (MAPK) pathways respond to a variety of disparate signals which induce differentiation, proliferation, or changes in intracellular enzyme regulation. Recent advances have identified two new mammalian MAPK relatives, JNK1 and p38, and the pathways which are responsible for their activation.

引用

收藏

页码：798 / 805

页数：8

相关论文

共 79 条

[1] ACTIVATING TRANSCRIPTION FACTOR-II DNA-BINDING ACTIVITY IS STIMULATED BY PHOSPHORYLATION CATALYZED BY P42 AND P54 MICROTUBULE-ASSOCIATED PROTEIN-KINASES [J].

ABDELHAFIZ, HA ;

HEASLEY, LE ;

KYRIAKIS, JM ;

AVRUCH, J ;

KROLL, DJ ;

JOHNSON, GL ;

HOEFFLER, JP .

MOLECULAR ENDOCRINOLOGY, 1992, 6 (12) :2079-2089

[2]

ALESSI DR, 1993, ONCOGENE, V8, P2015

[3] IDENTIFICATION OF THE SITES IN MAP KINASE KINASE-1 PHOSPHORYLATED BY P74(RAF-1) [J].

ALESSI, DR ;

SAITO, Y ;

CAMPBELL, DG ;

COHEN, P ;

SITHANANDAM, G ;

RAPP, U ;

ASHWORTH, A ;

MARSHALL, CJ ;

COWLEY, S .

EMBO JOURNAL, 1994, 13 (07) :1610-1619

[4] INACTIVATION OF P42 MAP KINASE BY PROTEIN PHOSPHATASE 2A AND A PROTEIN-TYROSINE-PHOSPHATASE, BUT NOT CL100, IN VARIOUS CELL-LINES [J].

ALESSI, DR ;

GOMEZ, N ;

MOORHEAD, C ;

LEWIS, T ;

KEYSE, SM ;

COHEN, P .

CURRENT BIOLOGY, 1995, 5 (03) :283-295

[5] REQUIREMENT FOR INTEGRATION OF SIGNALS FROM 2 DISTINCT PHOSPHORYLATION PATHWAYS FOR ACTIVATION OF MAP KINASE [J].

ANDERSON, NG ;

MALLER, JL ;

TONKS, NK ;

STURGILL, TW .

NATURE, 1990, 343 (6259) :651-653

[6] RAF MEETS RAS - COMPLETING THE FRAMEWORK OF A SIGNAL-TRANSDUCTION PATHWAY [J].

AVRUCH, J ;

ZHANG, XF ;

KYRIAKIS, JM .

TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (07) :279-283

[7] MAMMALIAN MITOGEN-ACTIVATED PROTEIN-KINASE KINASE KINASE (MEKK) CAN FUNCTION IN A YEAST MITOGEN-ACTIVATED PROTEIN-KINASE PATHWAY DOWNSTREAM OF PROTEIN-KINASE-C [J].

BLUMER, KJ ;

JOHNSON, GL ;

LANGECARTER, CA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) :4925-4929

[8] REGULATION OF PROTEIN SERINE-THREONINE PHOSPHATASE TYPE-2A BY TYROSINE PHOSPHORYLATION [J].

CHEN, J ;

MARTIN, BL ;

BRAUTIGAN, DL .

SCIENCE, 1992, 257 (5074) :1261-1264

[9]

CHEN RH, 1993, P NATL ACAD SCI USA, V9, P10952

[10] THE SMALL GTP-BINDING PROTEINS RAC1 AND CDC42 REGULATE THE ACTIVITY OF THE JNK/SAPK SIGNALING PATHWAY [J].

COSO, OA ;

CHIARIELLO, M ;

YU, JC ;

TERAMOTO, H ;

CRESPO, P ;

XU, NG ;

MIKI, T ;

GUTKIND, JS .

CELL, 1995, 81 (07) :1137-1146

← 1 2 3 4 5 6 7 8 →