ENDOMETRIAL THICKNESS AFTER MENOPAUSE - EFFECT OF HORMONE REPLACEMENT

被引:80
作者
LIN, MC
GOSINK, BB
WOLF, SI
FELDESMAN, MR
STUENKEL, CA
BRALY, PS
PRETORIUS, DH
机构
[1] UNIV CALIF SAN DIEGO, MED CTR,DEPT RADIOL,DIV ULTRASOUND H759, 225 DICKINSON ST, SAN DIEGO, CA 92103 USA
[2] KAISER SUNNYSIDE MED CTR, DEPT RADIOL, CLACKAMAS, OR USA
[3] PORTLAND STATE UNIV, DEPT ANTHROPOL, PORTLAND, OR 97207 USA
关键词
HORMONES; UTERINE NEOPLASMS; DIAGNOSIS; US STUDIES; UTERUS; ENDOMETRIUM;
D O I
10.1148/radiology.180.2.1829843
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Ultrasound (US) images of the pelvis were evaluated in 112 asymptomatic postmenopausal women to investigate the normal range of endometrial thickness (double-layer measurement) and the effect of hormone replacement on these measurements. Twenty-one patients (19%) had endometrial thickness greater than 0.8 cm. One patient, with an endometrial thickness of 2.5 cm, had endometrial carcinoma. Consideration of the known actions of estrogen and progestogen on the endometrium led the authors to believe that the clinical significance of an endometrium measuring more than 0.8 cm depends on the patient's hormonal status. Among asymptomatic postmenopausal women with an endometrial thickness between 0.8 and 1.5 cm, those receiving unopposed estrogen or continuous estrogen and progestogen need to undergo dilatation and curettage (D&C) or biopsy and those receiving no hormones or receiving sequential estrogen and progestogen should be encouraged to undergo D&C or biopsy. If a patient in one of the latter two groups is unwilling to undergo an invasive procedure, then US examination at 3-month intervals is acceptable. Any patient with endometrial thickness of at least 1.5 cm should undergo histologic diagnosis, regardless of symptoms or hormone status.
引用
收藏
页码:427 / 432
页数:6
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