OPTIMAL DOSE OF LIGNOCAINE FOR PREVENTING PAIN ON INJECTION OF PROPOFOL

被引：54

作者：

GEHAN, G ^{[1
]}

KAROUBI, P ^{[1
]}

QUINET, F ^{[1
]}

LEROY, A ^{[1
]}

RATHAT, C ^{[1
]}

POURRIAT, JL ^{[1
]}

机构：

[1] UNIV PARIS 13,CHU AVICENNE JEAN VERDIER,DEPT ANESTHESIE REANIMAT,F-93000 BOBIGNY,FRANCE

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1991年 / 66卷 / 03期

关键词：

ANESTHETICS; INTRAVENOUS; PROPOFOL; COMPLICATIONS; PAIN;

D O I：

10.1093/bja/66.3.324

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The purpose of this study was to define the optimum dose of lignocaine required to reduce pain on injection of propofol. We conducted a prospective, randomized, double-blind trial on 310 patients undergoing anaesthesia. Patients were allocated to four groups according to the lignocaine dosage: group A (control), no lignocaine; group B, lignocaine 0.1 mg kg-1; group C, lignocaine 0.2 mg kg-1; group D, lignocaine 0.4 mg kg-1. Our results showed that a dose of lignocaine 0.1 mg kg-1 significantly reduced the incidence of pain and that there was no improvement when the dose was increased.

引用

页码：324 / 326

页数：3

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