ENHANCEMENT OF MHC CLASS-II ANTIGEN EXPRESSION BY EXPOSURE TO CANDIDA-ALBICANS

被引：5

作者：

ASHMAN, RB

机构：

[1] Pathology Department, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands

来源：

IMMUNOLOGY LETTERS | 1991年 / 30卷 / 02期

关键词：

CANDIDA-ALBICANS; MHC ANTIGEN; IMMUNOREGULATION;

D O I：

10.1016/0165-2478(91)90034-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In oral infections with the yeast Candida albicans, the expression of MHC class II antigens on keratinocytes has been reported to be enhanced. In the present experiments, exposure to C. albicans or its products in vitro was found to increase the expression of class II MHC antigens on thioglycollate-induced mouse macrophages, and on LK cells (an antigen-presenting cell line). The implications of this finding for the understanding of immuno-regulation and susceptibility to C. albicans infection are discussed.

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页码：255 / 260

页数：6

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