DRY, MOIST, AND WET SKIN WOUND REPAIR

被引:124
作者
VOGT, PM [1 ]
ANDREE, C [1 ]
BREUING, K [1 ]
LIU, PY [1 ]
SLAMA, J [1 ]
HELO, G [1 ]
ERIKSSON, E [1 ]
机构
[1] HARVARD UNIV,SCH MED,BOSTON,MA
关键词
D O I
10.1097/00000637-199505000-00007
中图分类号
R61 [外科手术学];
学科分类号
摘要
Effects of wet (saline in a vinyl chamber), moist (hydrocolloid dressing), and dry (sterile gauze dressing) environments on wound repair were studied in a porcine partial-thickness wound model. Chambers were exchanged and refilled daily with normal saline containing penicillin G (100 U/ml) and streptomycin (100 mu g/ml). Hydrocolloid and gauze dressings were kept in place until biopsy of the wound site. Wounds in wet, moist, and dry environments were completely epithelialized on days 6, 7, and 8, respectively, Thickness of the epidermis in wet, moist, and dry wounds was 204 +/- 23, 141 +/- 12, and 129 +/- 18 (mean +/- SEM), respectively, Moist wounds had more subepidermal inflammatory cells than wet wounds. In comparison to dry wounds, the moist or the wet healing environment resulted in less necrosis and faster and better quality of healing in the formation of the newly regenerated epidermis.
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页码:493 / 499
页数:7
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