2-AMINOOXAZOLINES .1. CRYSTAL AND MOLECULAR-STRUCTURE OF 5-(1-ARYL-4-PIPERAZINO)METHYL-SUBSTITUTED DERIVATIVES WITH ANTIDEPRESSANT ACTIVITY

被引:15
作者
JARRY, C [1 ]
BOSC, JJ [1 ]
OUHABI, J [1 ]
CARPY, A [1 ]
机构
[1] UNIV BORDEAUX 2,FAC SCI PHARMACEUT,CNRS,URA 50,F-33076 BORDEAUX,FRANCE
关键词
D O I
10.1002/ardp.19903230306
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The structure of two 5‐(1‐aryl‐4‐piperazino)methyl‐2‐aminooxazolines were determined by X‐ray crystallography. An amino form is preponderant in a free base whereas an imino form is preponderant in a salt. The molecular conformations were studied by molecular mechanics. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
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页码:157 / 161
页数:5
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