LATENCY OF THE HUMAN HERPESVIRUSES

被引：5

作者：

CROEN, KD

机构：

来源：

ANNUAL REVIEW OF MEDICINE | 1991年 / 42卷

关键词：

TRANSCRIPTION; REACTIVATION; GENOME; LYTIC; IMMEDIATE-EARLY GENES;

D O I：

10.1146/annurev.med.42.1.61

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The herpesviruses are ubiquitous pathogens that establish latent infections and can reactivate to produce recurrent disease. The fact that clinical recurrences are infrequent in most healthy individuals indicates that potent regulatory mechanisms must exist to ensure viral latency. Rapid progress is being made toward understanding the pathogenesis of latency and reactivation and is the subject of this review.

引用

收藏

页码：61 / 67

页数：7

相关论文

共 26 条

[1]

Ahmed R., 1990, VIROLOGY, P241

[2]

ALLDAY MJ, 1988, LANCET, V1, P855

[3] LATENCY COMES OF AGE FOR HERPESVIRUSES [J].

BAICHWAL, VR ;

SUGDEN, B .

CELL, 1988, 52 (06) :787-789

[4] DETECTION OF PSEUDORABIES VIRUS TRANSCRIPTS IN TRIGEMINAL GANGLIA OF LATENTLY INFECTED SWINE [J].

CHEUNG, AK .

JOURNAL OF VIROLOGY, 1989, 63 (07) :2908-2913

[5] HERPES-SIMPLEX VIRUS TYPE-2 ESTABLISHES LATENCY IN THE MOUSE FOOTPAD [J].

CLEMENTS, GB ;

SUBAKSHARPE, JH .

JOURNAL OF GENERAL VIROLOGY, 1988, 69 :375-383

[6] LATENT HERPES-SIMPLEX VIRUS IN HUMAN TRIGEMINAL GANGLIA - DETECTION OF AN IMMEDIATE EARLY GENE ANTISENSE TRANSCRIPT BY INSITU HYBRIDIZATION [J].

CROEN, KD ;

OSTROVE, JM ;

DRAGOVIC, LJ ;

SMIALEK, JE ;

STRAUS, SE .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (23) :1427-1432

[7] PATTERNS OF GENE-EXPRESSION AND SITES OF LATENCY IN HUMAN NERVE GANGLIA ARE DIFFERENT FOR VARICELLA-ZOSTER AND HERPES-SIMPLEX VIRUSES [J].

CROEN, KD ;

OSTROVE, JM ;

DRAGOVIC, LJ ;

STRAUS, SE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (24) :9773-9777

[8] EPSTEIN-BARR-VIRUS LATENT MEMBRANE-PROTEIN INHIBITS HUMAN EPITHELIAL-CELL DIFFERENTIATION [J].

DAWSON, CW ;

RICKINSON, AB ;

YOUNG, LS .

NATURE, 1990, 344 (6268) :777-780

[9] SPECIFIC EFFECT OF INTERFERON ON THE HERPES-SIMPLEX VIRUS TYPE-1 TRANSACTIVATION EVENT [J].

DESTASIO, PR ;

TAYLOR, MW .

JOURNAL OF VIROLOGY, 1990, 64 (06) :2588-2593

[10] HERPES-SIMPLEX VIRUS ISOLATION IN CHRONIC STROMAL KERATITIS - HUMAN AND LABORATORY STUDIES [J].

EASTY, DL ;

SHIMELD, C ;

CLAOUE, CMP ;

MENAGE, M .

CURRENT EYE RESEARCH, 1987, 6 (01) :69-74