CDNA SEQUENCE FOR RAT DERMATAN SULFATE PROTEOGLYCAN-II (DECORIN)

被引：28

作者：

ABRAMSON, SR

WOESSNER, JF

机构：

[1] UNIV MIAMI,SCH MED,DEPT BIOCHEM & MOLEC BIOL,REPSCEND LABS,MIAMI,FL 33101

[2] UNIV MIAMI,SCH MED,DEPT MED,MIAMI,FL 33101

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1132卷 / 02期

关键词：

DECORIN; PROTEOGLYCAN; CDNA SEQUENCE; (RAT);

D O I：

10.1016/0167-4781(92)90019-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA clone for dermatan sulfate proteoglycan-II, or decorin, has been isolated from a rat uterus library and sequenced. The cDNA and deduced amino acid sequences are 79 and 77% identical to the previously reported human and bovine sequences, respectively. The rat protein contains potential attachment sites for two glycosaminoglycan chains and four N-linked oligosaccharides, six conserved cysteine residues and multiple repeats of a leucine-rich sequence, LXXLXLXXNXL/I. Overlapping the C-end of one of these repeats is an NKISK sequence, which has been implicated in binding to fibronectin.

引用

页码：225 / 227

页数：3

共 14 条

[1]

BIDANSET DJ, 1992, J BIOL CHEM, V267, P5250

[2]

BLOCHBERGER TC, 1992, J BIOL CHEM, V267, P347

[3] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE CDNA FOR SMALL PROTEOGLYCAN-II OF BOVINE BONE [J].