BORON ANALOGS OF VALINE, LEUCINE, AND ISOLEUCINE - SYNTHESIS OF AMINE-ALKYL(C-ALKOXYCARBONYL)BORANES AND AMINE-ALKYL(N,N-DIETHYLCARBAMOYL)BORANES

被引：13

作者：

SUTTON, CH ^{[1
]}

BAIZE, MW ^{[1
]}

TODD, LJ ^{[1
]}

机构：

[1] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47405

来源：

INORGANIC CHEMISTRY | 1994年 / 33卷 / 19期

关键词：

D O I：

10.1021/ic00097a006

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Alkylation of amine-alkyl(C-allcoxy-N-ethylcyano)borane with Et(3)OBF(4) resulted in the isolation of amine-alkyl(C-alkoxy-N,N-diethyrcyano)borane tetrafluoroborates, which, upon aqueous base hydrolysis, yielded both the amine-alkyl(C-alkoxycarbonyl)borane and the amine-alkyl(N,N-diethylcarbamoyl)borane in varyng ratios. Amine-alkyl(C-alkoxycarbonyl)boranes (amine = quinuclidine, pyridine; alkyl = iBu, iPr, sBu; alkoxy R = Me, benzyl) representative of several amino acid analogues have been isolated and characterized. These are the first ester derivatives of a boron analog other than glycine.

引用

页码：4221 / 4225

页数：5

共 30 条

[1] TRANSFER HYDROGENATION - CONVENIENT METHOD FOR REMOVAL OF SOME COMMONLY USED PROTECTING GROUPS IN PEPTIDE-SYNTHESIS [J].