SYNTHESIS AND INVITRO ANTIVIRAL ACTIVITY OF 3'-O-ACYL DERIVATIVES OF 5'-AMINO-5'-DEOXYTHYMIDINE - POTENTIAL PRODRUGS FOR TOPICAL APPLICATION

被引：8

作者：

LIN, TS ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,CTR COMPREHENS CANC,NEW HAVEN,CT 06510

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1984年 / 73卷 / 11期

关键词：

D O I：

10.1002/jps.2600731120

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1568 / 1571

页数：4

共 10 条

[1] PRODRUGS OF 9-BETA-D-ARABINOFURANOSYLADENINE .1. SYNTHESIS AND EVALUATION OF SOME 5'-(O-ACYL) DERIVATIVES [J].

BAKER, DC ;

HASKELL, TH ;

PUTT, SR .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (12) :1218-1221

[2] 5'-AMINO-5'-DEOXYTHYMIDINE - SYNTHESIS, SPECIFIC PHOSPHORYLATION BY HERPESVIRUS THYMIDINE KINASE, AND STABILITY TO PH OF THE ENZYMICALLY FORMED DIPHOSPHATE DERIVATIVE [J].

CHEN, MS ;

SHIAU, GT ;

PRUSOFF, WH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1980, 18 (03) :433-436

[3]

CHEN MS, 1976, J BIOL CHEM, V251, P4833

[4] PREPARATION AND ANTIMALARIAL ACTIVITY OF SOME DERIVATIVES OF 6-BROMO-ALPHA-(DI-N-HEPTYLAMINOMETHYL)-9-PHENANTHRENEMETHANOL [J].

HARMON, RE ;

LIN, TS ;

GUPTA, SK .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (08) :940-942

[5]

HETTINGER ME, 1981, ARCH OPHTHALMOL-CHIC, V99, P1618

[6] CAFFEINE COMPLEXES WITH LOW WATER SOLUBILITY - SYNTHESIS AND DISSOLUTION RATES OF 1-1 AND 1-2 CAFFEINE-GENTISIC ACID COMPLEXES [J].

HIGUCHI, T ;

PITMAN, IH .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1973, 62 (01) :55-58

[7] SYNTHESIS AND ANTIVIRAL ACTIVITY OF 5-SUBSTITUTED AND 5'-SUBSTITUTED THYMIDINE ANALOGS [J].

LIN, TS ;

NEENAN, JP ;

CHENG, YC ;

PRUSOFF, WH ;

WARD, DC .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (04) :495-498

[8] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SEVERAL AMINO ANALOGS OF THYMIDINE [J].

LIN, TS ;

PRUSOFF, WH .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (01) :109-112

[9]

PAVANLANGSTON D, 1982, P SOC EXP BIOL MED, V170, P1

[10]

YU CD, 1979, J PHARM SCI, V68, P1341

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