RYANODYL 3-(PYRIDINE-3-CARBOXYLATE) - A NOVEL RYANOID FROM RYANIA INSECTICIDE

被引：19

作者：

JEFFERIES, PR

TOIA, RF

CASIDA, JE

机构：

[1] Pesticide Chemistry and Toxicology Laboratory, Department of Entomological Sciences, University of California, Berkeley

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 04期

关键词：

D O I：

10.1021/np50076a043

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Ryanodyl 3-(pyridine-3-carboxylate) [3] was isolated as a minor component from the wet CHCl3 extract of Ryania insecticide, and its structure was assigned by chemical and spectroscopic methods. This compound is essentially inactive compared with ryanodine for insecticidal activity against Musca domestica adults and Tribolium castaneum larvae, for toxicity to mice, and for competition with [H-3]ryanodine at the Ca2+-ryanodine receptor complex of skeletal muscle.

引用

页码：1147 / 1149

页数：3

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