METHOTREXATE ANALOGS .27. DUAL INHIBITION OF DIHYDROFOLATE-REDUCTASE AND FOLYLPOLYGLUTAMATE SYNTHETASE BY METHOTREXATE AND AMINOPTERIN ANALOGS WITH A GAMMA-PHOSPHONATE GROUP IN THE SIDE-CHAIN

被引：19

作者：

ROSOWSKY, A

MORAN, RC

FORSCH, RA

RADIKESMITH, M

COLMAN, PD

WICK, MM

FREISHEIM, JH

机构：

[1] HARVARD UNIV,SCH MED,DEPT PHARMACOL,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,DEPT DERMATOL,BOSTON,MA 02115

[3] CHILDRENS HOSP,DIV HEMATOL ONCOL,LOS ANGELES,CA 90027

[4] MED COLL OHIO,DEPT BIOCHEM,TOLEDO,OH 43699

来源：

BIOCHEMICAL PHARMACOLOGY | 1986年 / 35卷 / 19期

关键词：

D O I：

10.1016/0006-2952(86)90431-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3327 / 3333

页数：7

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