FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF HUMAN AUDITORY-CORTEX

被引:332
作者
BINDER, JR
RAO, SM
HAMMEKE, TA
YETKIN, FZ
JESMANOWICZ, A
BANDETTINI, PA
WONG, EC
ESTKOWSKI, LD
GOLDSTEIN, MD
HAUGHTON, VM
HYDE, JS
机构
[1] MED COLL WISCONSIN,DEPT RADIOL,MILWAUKEE,WI 53226
[2] MED COLL WISCONSIN,DEPT BIOPHYS,MILWAUKEE,WI
[3] MED COLL WISCONSIN,DEPT PSYCHIAT,MILWAUKEE,WI
关键词
D O I
10.1002/ana.410350606
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.
引用
收藏
页码:662 / 672
页数:11
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