ANTIATHEROSCLEROTIC AGENTS - A STRUCTURALLY NOVEL BIVALENT INHIBITOR OF ACYLCOA-CHOLESTEROL O-ACYLTRANSFERASE WITH SYSTEMIC ACTIVITY

被引：32

作者：

GAMMILL, RB

BELL, FP

BELL, LT

BISAHA, SN

WILSON, GJ

机构：

[1] Upjohn Laboratories, Upjohn Company Kalamazoo

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1990年 / 33卷 / 10期

关键词：

D O I：

10.1021/jm00172a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2685 / 2686

页数：2

共 32 条

[1] EFFECTS OF VARIOUS ANTIHYPERTENSIVE AGENTS ON LIPID-METABOLISM - ALTERATIONS IN THE PATTERN OF LIPIDS SYNTHESIZED FROM [C-14]OLEATE IN RAT-LIVER INVITRO [J].

BELL, FP .

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[2] THE EFFECT OF LIDOCAINE ON CHOLESTEROL INFLUX, ESTERIFICATION, AND ACCUMULATION IN CULTURED-CELLS [J].

BELL, FP ;

ROTHBLAT, GH ;

BAMBERGER, M .

CANADIAN JOURNAL OF BIOCHEMISTRY, 1982, 60 (10) :967-971

[3] EXCHANGEABILITY OF CHOLESTEROL BETWEEN SWINE SERUM LIPOPROTEINS AND ERTHROCYTES, IN-VITRO [J].

BELL, FP ;

SCHWARTZ, CJ .

BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 231 (03) :553-&

[4] EFFECT OF PHTHALATE ESTERS ON SERUM-CHOLESTEROL AND LIPID BIOSYNTHESIS IN LIVER, TESTES, AND EPIDIDYMAL FAT IN RAT AND RABBIT [J].

BELL, FP ;

PATT, CS ;

GILLIES, PJ .

LIPIDS, 1978, 13 (10) :673-678

[5] CHLORPROMAZINE INHIBITS ARTERIAL ACAT AND REDUCES ARTERIAL CHOLESTEROL AND CHOLESTERYL ESTER ACCUMULATION IN CHOLESTEROL-FED RABBITS [J].

BELL, FP ;

SCHAUB, RG .

ARTERIOSCLEROSIS, 1986, 6 (01) :42-49

[6] EFFECT OF CHLORPROMAZINE ON LIPID-METABOLISM IN AORTAS FROM CHOLESTEROL-FED RABBITS AND NORMAL RATS, INVITRO - INHIBITION OF STEROL ESTERIFICATION AND MODIFICATION OF PHOSPHOLIPID-SYNTHESIS [J].

BELL, FP .

EXPERIMENTAL AND MOLECULAR PATHOLOGY, 1983, 38 (03) :336-345

[7]

BELL FP, 1986, PHARM CONTROL HYPERL, P409

[8] PROPERTIES OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE IN AORTIC MICROSOMES FROM ATHEROSCLEROTIC RABBITS [J].

BRECHER, P ;

CHAN, CT .

BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 617 (03) :458-471

[9]

BROWN MS, 1980, J BIOL CHEM, V255, P9344

[10]

CHANG TY, 1983, ACYL COENZYME CHOLES, pCH15

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