PEPSTATIN-DERIVED INHIBITORS OF ASPARTIC PROTEINASES - A CLOSE LOOK AT AN APPARENT TRANSITION-STATE ANALOG INHIBITOR

被引：251

作者：

RICH, DH

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 03期

关键词：

D O I：

10.1021/jm00381a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：263 / 273

页数：11

共 75 条

[1]

Agarwal N., UNPUB

[2]

Antonov V K, 1977, Adv Exp Med Biol, V95, P179

[3]

ANTONOV VK, 1981, EUR J BIOCHEM, V117, P195

[4] MECHANISM OF PEPSIN CATALYSIS - GENERAL BASE CATALYSIS BY ACTIVE-SITE CARBOXYLATE ION [J].

ANTONOV, VK ;

GINODMAN, LM ;

KAPITANNIKOV, YV ;

BARSHEVSKAYA, TN ;

GUROVA, AG ;

RUMSH, LD .

FEBS LETTERS, 1978, 88 (01) :87-90

[5]

AOYAGI T, 1978, BIOACTIVE PEPTIDES P, P129

[6] PHOSPHINIC ACID DIPEPTIDE ANALOGS - POTENT, SLOW-BINDING INHIBITORS OF ASPARTIC PEPTIDASES [J].

BARTLETT, PA ;

KEZER, WB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (15) :4282-4283

[7] PHOSPHONAMIDATES AS TRANSITION-STATE ANALOG INHIBITORS OF THERMOLYSIN [J].

BARTLETT, PA ;

MARLOWE, CK .

BIOCHEMISTRY, 1983, 22 (20) :4618-4624

[8] MECHANISM OF ACTION OF PROTEOLYTIC ENZYMES [J].

BENDER, ML ;

KEZDY, FJ .

ANNUAL REVIEW OF BIOCHEMISTRY, 1965, 34 :49-&

[9]

BERNATOWICZ MS, 1984, THESIS U WISCONSIN M

[10] NOVEL RENIN INHIBITORS CONTAINING THE AMINO-ACID STATINE [J].

BOGER, J ;

LOHR, NS ;

ULM, EH ;

POE, M ;

BLAINE, EH ;

FANELLI, GM ;

LIN, TY ;

PAYNE, LS ;

SCHORN, TW ;

LAMONT, BI ;

VASSIL, TC ;

STABILITO, II ;

VEBER, DF ;

RICH, DH ;

BOPARI, AS .

NATURE, 1983, 303 (5912) :81-84

← 1 2 3 4 5 6 7 8 →