EFFICIENT SYNTHESIS OF PORPHYRIN DIMERS WITH CARBON-CARBON LINKAGES

被引：53

作者：

PANDEY, RK

SHIAU, FY

MEDFORTH, CJ

DOUGHERTY, TJ

SMITH, KM

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

[2] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT RADIAT BIOL,BUFFALO,NY 14263

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)94628-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Porphyrin dimers with carbon-carbon linkages were synthesized in excellent yield from (1-hydroxyethyl)porphyrins by treatment with triflic acid under mild reaction conditions. The method is used to prepare dimers which show promising tumorcidal activity in photodynamic therapy. © 1990.

引用

页码：789 / 792

页数：4

共 16 条

[1]

DOUGHERTY TJ, 1983, ADV EXP MED BIOL, V160, P3

[2] PHOTODYNAMIC THERAPY (PDT) OF MALIGNANT-TUMORS [J].