ANALYSIS OF ANCIENT BONE DNA - TECHNIQUES AND APPLICATIONS

被引：83

作者：

HAGELBERG, E

BELL, LS

ALLEN, T

BOYDE, A

JONES, SJ

CLEGG, JB

机构：

[1] UNIV LONDON UNIV COLL,DEPT ANAT & DEV ANAT,HARD TISSUE RES UNIT,LONDON WC1E 6BT,ENGLAND

[2] OXFORD ARCHAEOL UNIT,OXFORD OX1 2EP,ENGLAND

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 1991年 / 333卷 / 1268期

关键词：

D O I：

10.1098/rstb.1991.0090

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The analysis of DNA from ancient bone has numerous applications in archaeology and molecular evolution. Significant amounts of genetic information can be recovered from ancient bone: mitochondrial DNA sequences of 800 base pairs have been amplified from a 750-year-old human femur by using the polymerase chain reaction. DNA recovery varies considerably between bone samples and is not dependent on the age of the specimen. We present the results of a study on a small number of bones from a mediaeval and a 17th-century cemetery in Abingdon showing the relation between gross preservation, microscopic preservation and DNA recovery.

引用

页码：399 / 407

页数：9

共 36 条

[1]

ALLEN T, 1989, S MIDL ARCHAEOL, V19, P44

[2]

Allen T., 1990, S MIDL ARCHAEOL, V20, P73

[3]

Allen T., 1990, CURRENT ARCHAEOL, V121, P24

[4] SEQUENCE AND ORGANIZATION OF THE HUMAN MITOCHONDRIAL GENOME [J].

ANDERSON, S ;

BANKIER, AT ;

BARRELL, BG ;

DEBRUIJN, MHL ;

COULSON, AR ;

DROUIN, J ;

EPERON, IC ;

NIERLICH, DP ;

ROE, BA ;

SANGER, F ;

SCHREIER, PH ;

SMITH, AJH ;

STADEN, R ;

YOUNG, IG .

NATURE, 1981, 290 (5806) :457-465

[5]

ASCENZI A, 1984, J HUM EVOL, V7, P409

[6] PALEOPATHOLOGY AND DIAGENESIS - AN SEM EVALUATION OF STRUCTURAL-CHANGES USING BACKSCATTERED ELECTRON IMAGING [J].

BELL, LS .

JOURNAL OF ARCHAEOLOGICAL SCIENCE, 1990, 17 (01) :85-102

[7]

BELL LS, 1991, IN PRESS SCANNING, V13

[8]

Brothwell DR., 1981, DIGGING BONES EXCAVA, P64, DOI [10.1002/ajpa.1330560425, DOI 10.1002/AJPA.1330560425]

[9]

CLEMENT AJ, 1963, DENTAL ANTHR

[10]

Garl A.N., 1989, APPL GEOCHEM, V4, P215, DOI DOI 10.1016/0883-2927(89)90021-8

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