THE CELLULAR REPRODUCTION IN PHYSIOLOGICAL AND REPARATIVE LIVER-REGENERATION

被引:5
作者
GEISLER, A
STILLER, K
MACHNIK, G
机构
[1] UNIV JENA,INST PATHOL,D-07743 JENA,GERMANY
[2] UNIV JENA,SURG CLIN,O-6900 JENA,GERMANY
关键词
REGENERATION; LIVER; LIVER REGENERATION; STEM CELLS;
D O I
10.1016/S0940-2993(11)80093-X
中图分类号
R36 [病理学];
学科分类号
100104 [病理学与病理生理学];
摘要
The liver regeneration of male rats was examined autoradiographically under physiological and reparative conditions. The reparative regeneration was induced by a single injection of allylalcohol intraperitoneally. In both forms of regeneration a displacement of tritiated thymidine-marked hepatocytes from the periportal field to the perivenous field of the liver acinus could be recognized. The velocity of the cell migration after allylalcohol administration was higher than under physiological conditions. Physiological and reparative liver regeneration do not exclude each other but obviously coexist. A more intensively to be examined hepatocellular stem cell concept gains importance.
引用
收藏
页码:247 / 250
页数:4
相关论文
共 9 条
[1]
ALTMANN HW, 1966, VERH DTSCH GES PATH, V50, P15
[2]
ARBER N, 1988, LIVER, V8, P80
[3]
CELL-KINETICS IN LIVER OF RATS UNDER NORMAL AND ABNORMAL DIETARY CONDITIONS - AUTORADIOGRAPHIC STUDY BY MEANS OF [H-3]THYMIDINE [J].
BLIKKENDAALLIEFTINCK, LF ;
KOOIJ, M ;
KRAMER, MF ;
DENOTTER, W .
EXPERIMENTAL AND MOLECULAR PATHOLOGY, 1977, 26 (02) :184-192
[4]
EDER M, 1990, ALLGEMEINE PATHOLOGI, P239
[5]
KINETICS OF CELLULAR PROLIFERATION IN REGENERATING LIVER [J].
FABRIKANT, JI .
JOURNAL OF CELL BIOLOGY, 1968, 36 (03) :551-+
[6]
GRISHAM JW, 1962, CANCER RES, V22, P842
[7]
MARLEEN P, 1989, Pathology Research and Practice, V184, P69
[8]
LIVER-REGENERATION - MOLECULAR MECHANISMS OF GROWTH-CONTROL [J].
MICHALOPOULOS, GK .
FASEB JOURNAL, 1990, 4 (02) :176-187
[9]
AUTORADIOGRAPHISCHE UNTERSUCHUNGEN MIT 3H-THYMIDIN AN DER REGENERIERENDEN RATTENLEBER [J].
STOCKER, E ;
PFEIFER, U .
ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE, 1967, 79 (03) :374-+