(+)-(S)-DIHYDROAERUGINOIC ACID, AN INHIBITOR OF SEPTORIA-TRITICI AND OTHER PHYTOPATHOGENIC FUNGI AND BACTERIA, PRODUCED BY PSEUDOMONAS-FLUORESCENS

被引：46

作者：

CARMI, R

CARMELI, S

LEVY, E

GOUGH, FJ

机构：

[1] TEL AVIV UNIV,RAYMOND & BEVERLY SACKLER FAC EXACT SCI,SCH CHEM,IL-69978 TEL AVIV,ISRAEL

[2] MINIST AGR,DEPT PLANT PROTECT & INSPECT,IL-50250 BET DAGAN,ISRAEL

[3] USDA,ARS,PLANT SCI & WATER CONSERVAT LAB,STILLWATER,OK 74075

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 09期

关键词：

D O I：

10.1021/np50111a002

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three antibiotics were isolated from a CH2Cl2 extract of the liquid culture of Pseudomonas fluorescens strain PFM2. Two of the antibiotics were identified as 2,4-diacetylphloroglucinol and pyoluterin. The structure elucidation, absolute stereochemistry, synthesis, and biological activities of the new antibiotic (+)-(S)dihydroaeruginoic acid IU are reported.

引用

收藏

页码：1200 / 1205

页数：6

相关论文

共 19 条

[1] REVISED STRUCTURE FOR THE PHENAZINE ANTIBIOTIC FROM PSEUDOMONAS-FLUORESCENS 2-79 (NRRL B-15132) [J].

BRISBANE, PG ;

JANIK, LJ ;

TATE, ME ;

WARREN, RFO .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (12) :1967-1971

[2] TANTAZOLES - UNUSUAL CYTOTOXIC ALKALOIDS FROM THE BLUE-GREEN-ALGA SCYTONEMA-MIRABILE [J].

CARMELI, S ;

MOORE, RE ;

PATTERSON, GML ;

CORBETT, TH ;

VALERIOTE, FA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (22) :8195-8197

[3] PYOCHELIN - NOVEL STRUCTURE OF AN IRON-CHELATING GROWTH PROMOTER FOR PSEUDOMONAS-AERUGINOSA [J].

COX, CD ;

RINEHART, KL ;

MOORE, ML ;

COOK, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4256-4260

[4]

Easson A. P. T., 1931, J CHEM SOC, P2991

[5]

ELLIOT GT, 1988, CANCER CHEMOTH PHARM, V21, P233

[6] INVITRO ANTIPROLIFERATIVE ACTIVITY OF 4-SUBSTITUTED 2-(2-HYDROXYPHENYL)THIAZOLINES ON MURINE LEUKEMIA-CELLS [J].

ELLIOTT, GT ;

NAGLE, WA ;

KELLY, KF ;

MCCOLLOUGH, D ;

BONA, RL ;

BURNS, ER .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (05) :1039-1043

[7] CHARACTERIZATION OF AN ANTIBIOTIC PRODUCED BY A STRAIN OF PSEUDOMONAS-FLUORESCENS INHIBITORY TO GAEUMANNOMYCES-GRAMINIS VAR TRITICI AND PYTHIUM SPP [J].

GURUSIDDAIAH, S ;

WELLER, DM ;

SARKAR, A ;

COOK, RJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 29 (03) :488-495

[8]

HOVEYDER HR, 1992, TETRAHEDRON, V48, P521

[9] SUPPRESSION OF PYTHIUM-ULTIMUM-INDUCED DAMPING-OFF OF COTTON SEEDLINGS BY PSEUDOMONAS-FLUORESCENS AND ITS ANTIBIOTIC, PYOLUTEORIN [J].

HOWELL, CR ;

STIPANOVIC, RD .

PHYTOPATHOLOGY, 1980, 70 (08) :712-715

[10] PATTERN OF PHENAZINE PIGMENT PRODUCTION BY A STRAIN OF PSEUDOMONAS-AERUGINOSA [J].

KANNER, D ;

GERBER, NN ;

BARTHA, R .

JOURNAL OF BACTERIOLOGY, 1978, 134 (02) :690-692