EVIDENCE FOR A 2,3-EPOXIDE AS AN INTERMEDIATE IN MICROSOMAL METABOLISM OF BENZO[A]PYRENE TO 3-HYDROXYBENZO[A]PYRENE

被引：54

作者：

YANG, SK

ROLLER, PP

FU, PP

HARVEY, RG

GELBOIN, HV

机构：

[1] NCI,CHEM BRANCH,BETHESDA,MD 20014

[2] NCI,CARCINOGEN METAB & TOXICOL BRANCH,BETHESDA,MD 20014

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1977年 / 77卷 / 04期

关键词：

D O I：

10.1016/S0006-291X(77)80103-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1176 / 1182

页数：7

共 29 条

[1] METABOLISM OF 3,4-BENZOPYRENE [J].

BERENBLUM, I ;

SCHOENTAL, R .

SCIENCE, 1955, 122 (3167) :470-470

[2]

Berenblum I, 1943, CANCER RES, V3, P151

[3]

CASU B, 1951, Tumori, V37, P527

[4]

Chambers J. G., 1941, BIOCHEM J, V35, P1270

[5] BENZO(A)PYREN-3-YL HYDROGEN SULFATE, A MAJOR ETHYL ACETATE-EXTRACTABLE METABOLITE OF BENZO(A)PYRENE IN HUMAN, HAMSTER AND RAT LUNG CULTURES [J].

COHEN, GM ;

HAWS, SM ;

MOORE, BP ;

BRIDGES, JW .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (23) :2561-2570

[6]

CONNEY AH, 1957, J BIOL CHEM, V228, P753

[7]

COOK JW, 1950, J CHEM SOC, P1112, DOI 10.1039/jr9500001112

[8] SEPARATION OF TEN BENZO(A)PYRENE PHENOLS BY RECYCLE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY AND IDENTIFICATION OF FOUR PHENOLS AS METABOLITES [J].

CROY, RG ;

SELKIRK, JK ;

HARVEY, RG ;

ENGEL, JF ;

GELBOIN, HV .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (02) :227-230

[9]

DALY JW, 1972, EXPERIENTIA, V28, P1129, DOI 10.1007/BF01946135

[10]

FALK HL, 1962, J NATL CANCER I, V28, P699

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