ROLE OF FINE-NEEDLE BIOPSY IN AN ATYPICAL CASE OF LUPUS LYMPHADENOPATHY

被引：4

作者：

LOO, CKC ^{[1
]}

GREENBERG, ML ^{[1
]}

机构：

[1] WESTMEAD HOSP,DEPT CYTOL,WESTMEAD,NSW 2145,AUSTRALIA

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1994年 / 10卷 / 02期

关键词：

FINE-NEEDLE BIOPSY; LUPUS LYMPHADENOPATHY; TINGIBLE BODY MACROPHAGES; KARYORRHECTIC DEBRIS; STEROIDS;

D O I：

10.1002/dc.2840100214

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Necrotizing lymphadenitis dominated by individual cell necrosis with tingible body macrophages and karyorrhectic nuclear debris is an unusual appearance in smears from fine-needle biopsies (FNB) of lymph nodes (Greenberg et al., Diagn Cytopathol 1993; 9.-443-447). These features together with a polymorphous population of lymphocytes, absent epithelioid histiocytes and neutrophils, suggest a possible diagnosis of either histiocytic necrotizing lymphadenitis (HNL) (syn. Kikuchi's Disease) or systemic lupus erythematosus (SLE). These were the cytologic features found in a FNB of a cervical lymph node in a 43-year-old female, treated for a mixed connective tissue disease. A presumptive diagnosis of an acute lupus lymphadenitis was made, based on the above features, and was subsequently confirmed by the presence of raised antinuclear antibodies as well as resolution of the lymphadenopathy on high dose steroids. (C) 1994 Wiley-Liss, Inc.

引用

页码：162 / 164

页数：3

共 9 条

[1]

Harvey AM, Schulman LE, Tumulty PA, Conley CL, Schoenrich EH, Systemic lupus erythematosus: Review of the literature and clinical analysis of 138 cases, Medicine (Baltimore), 33, pp. 291-437, (1954)

[2]

Ko YH, Lee JD, Fine‐needle aspiration cytology in lupus lymphadenopathy. A case report, Acta Cytol, 36, pp. 748-751, (1992)

[3]

Martin L, Fritzer M, Autoantibodies, Internal Medicine, pp. 1674-1680, (1990)

[4]

Kikuchi M, Yoshizumi T, Nakamura H, Necrotizing lymphadenitis: Possible acute toxoplasmic infection, Virchows Arch A Pathol Anat Histopathol, 376, pp. 247-253, (1977)

[5]

Sumiyoshi Y, Kikuchi M, Takeshita M, Ohshima K, Masuda Y, Alpha‐interferon in Kikuchi's disease, Virchows Arch B Cell Pathol, 61, pp. 201-207, (1991)

[6]

Ohshima K, Kikuchi M, Sumiyoshi Y, Et al., Proliferating cells in histiocytic necrotizing lymphadenitis, Virchows Arch B Cell Pathol, 61, pp. 97-100, (1991)

[7]

Dorfman RF, Berry GJ, Kikuchi's histiocytic necrotizing lymphadenitis: An analysis of 108 cases with emphasis on differential diagnosis, Semin Diagn Pathol, 5, pp. 329-345, (1988)

[8]

Paradinas FJ, Primary and secondary immune disorders, Lymph node biopsy interpretation, pp. 143-186, (1992)

[9]

Krishnan J, Danon AD, Frizzera G, Reactive lymphadenopathies and atypical lymphoproliferative disorders, Am J Clin Pathol, 99, pp. 385-396, (1993)

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