RELATIONSHIP BETWEEN AXONAL REGENERATION AND VASCULARITY IN TUBULATION - AN EXPERIMENTAL-STUDY IN RATS

被引：29

作者：

KAKINOKI, R

NISHIJIMA, N

UEBA, Y

OKA, M

YAMAMURO, T

机构：

[1] KYOTO UNIV, COLL MED TECHNOL, SAKYO KU, KYOTO 606, JAPAN

[2] KYOTO UNIV, BIOMED ENGN RES CTR, SAKYO KU, KYOTO 606, JAPAN

来源：

NEUROSCIENCE RESEARCH | 1995年 / 23卷 / 01期

关键词：

AXONAL REGENERATION; CAPILLARY; MICROANGIOGRAPHY; TUBULATION; VASCULARITY; VESSELS;

D O I：

10.1016/0168-0102(95)00923-H

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study investigated the effect of vascularity in a nerve conduit on peripheral nerve regeneration. The effect of three different types of tube (empty, blood vessel-containing and ligated vessel-containing) was compared using a rat sciatic nerve preparation with a 10-mm gap. Nerve regeneration through the vessel-containing tube was more efficient than in the other tubes 6 and 12 weeks after tubulation surgery, but there were no statistically significant differences among the three types of tube after 24 weeks. Electrophysiological, histological and microangiographic studies showed that vessels which were preinserted in the nerve conduit accelerated axonal regeneration through rapid capillary formation in the tube.

引用

页码：35 / 45

页数：11

共 31 条

[1] THE NERVES TO BLOOD-VESSELS SUPPLYING BLOOD TO NERVES - THE INNERVATION OF VASA NERVORUM [J].