IMMUNOSUPPRESSION - BINDING BY DESIGN

被引：11

作者：

RINGE, D

机构：

[1] BRANDEIS UNIV,DEPT CHEM,WALTHAM,MA 02254

[2] BRANDEIS UNIV,ROSENSTIEL BASIC MED SCI RES CTR,WALTHAM,MA 02254

来源：

NATURE | 1991年 / 351卷 / 6323期

关键词：

D O I：

10.1038/351185a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：185 / 186

页数：2

共 27 条

[1] 2 DISTINCT SIGNAL TRANSMISSION PATHWAYS IN LYMPHOCYTES-T ARE INHIBITED BY COMPLEXES FORMED BETWEEN AN IMMUNOPHILIN AND EITHER FK506 OR RAPAMYCIN [J].

BIERER, BE ;

MATTILA, PS ;

STANDAERT, RF ;

HERZENBERG, LA ;

BURAKOFF, SJ ;

CRABTREE, G ;

SCHREIBER, SL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (23) :9231-9235

[2] UNFOLDING AND REFOLDING OCCUR MUCH FASTER FOR A PROLINE-FREE PROTEIN THAN FOR MOST PROLINE-CONTAINING PROTEINS [J].

BRANDTS, JF ;

BRENNAN, M ;

LIN, LN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (10) :4178-4181

[3] CONTINGENT GENETIC REGULATORY EVENTS IN LYMPHOCYTE-T ACTIVATION [J].

CRABTREE, GR .

SCIENCE, 1989, 243 (4889) :355-361

[4]

DESJOILAIS R, 1990, P NATL ACAD SCI USA, V87, P6648

[5] CYCLOSPORINE-A SPECIFICALLY INHIBITS FUNCTION OF NUCLEAR PROTEINS INVOLVED IN T-CELL ACTIVATION [J].

EMMEL, EA ;

VERWEIJ, CL ;

DURAND, DB ;

HIGGINS, KM ;

LACY, E ;

CRABTREE, GR .

SCIENCE, 1989, 246 (4937) :1617-1620

[6]

FESIK SW, IN PRESS BIOCHEMISTR

[7] CYCLOPHILIN AND PEPTIDYL-PROLYL CIS-TRANS ISOMERASE ARE PROBABLY IDENTICAL PROTEINS [J].

FISCHER, G ;

WITTMANNLIEBOLD, B ;

LANG, K ;

KIEFHABER, T ;

SCHMID, FX .

NATURE, 1989, 337 (6206) :476-478

[8] A RECEPTOR FOR THE IMMUNOSUPPRESSANT FK506 IS A CIS-TRANS PEPTIDYL-PROLYL ISOMERASE [J].

HARDING, MW ;

GALAT, A ;

UEHLING, DE ;

SCHREIBER, SL .

NATURE, 1989, 341 (6244) :758-760

[9] SUBSTRATE SPECIFICITIES OF THE PEPTIDYL PROLYL CIS-TRANS ISOMERASE ACTIVITIES OF CYCLOPHILIN AND FK-506 BINDING-PROTEIN - EVIDENCE FOR THE EXISTENCE OF A FAMILY OF DISTINCT ENZYMES [J].

HARRISON, RK ;

STEIN, RL .

BIOCHEMISTRY, 1990, 29 (16) :3813-3816

[10] FOLDING OF RIBONUCLEASE-T1 .1. EXISTENCE OF MULTIPLE UNFOLDED STATES CREATED BY PROLINE ISOMERIZATION [J].

KIEFHABER, T ;

QUAAS, R ;

HAHN, U ;

SCHMID, FX .

BIOCHEMISTRY, 1990, 29 (12) :3053-3061

← 1 2 3 →