Measurement of exposure to environmental tobacco smoke in pregnant women

被引:44
作者
OConnor, TZ
Holford, TR
Leaderer, BP
Hammond, SK
Bracken, MB
机构
[1] YALE UNIV,SCH MED,DEPT EPIDEMIOL & PUBL HLTH,NEW HAVEN,CT 06510
[2] YALE UNIV,SCH MED,DEPT ANESTHESIOL,NEW HAVEN,CT 06510
[3] YALE UNIV,JOHN B PIERCE FDN LAB,NEW HAVEN,CT 06510
[4] UNIV CALIF BERKELEY,SCH PUBL HLTH,DIV ENVIRONM HLTH SCI,BERKELEY,CA
关键词
cotinine; nicotine; smoking; passive; tobacco smoke pollution;
D O I
10.1093/oxfordjournals.aje.a117599
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The authors compared three methods used to measure exposure to environmental tobacco smoke in pregnant women: personal air monitor, urine cotinine, and questionnaire. Environmental tobacco smoke exposure assessment methods were compared for agreement using Cohen's Kappa and the Spearman rank order correlation coefficient. Women who reported exposure had significantly higher levels of air nicotine concentration compared with women who reported no exposure, but urine cotinine did not differ. Air nicotine was, more highly correlated with home exposure (r = 0.34) than work exposure (r = 0.18). Urine cotinine correlated with work exposure (r = 0.14) but neither home nor social exposure. Agreement was ''fair'' (Kappa = 0.29) when self-reported exposure was compared with air monitor, but agreement was ''poor'' when urine cotinine was compared with serf-report (Kappa = 0.08) and air monitor (Kappa = 0.10). In low environmental tobacco smoke exposure environments, all three methods for measuring exposure may have a role, although modification to monitoring protocols will be needed to improve monitoring sensitivity and exposure classification.
引用
收藏
页码:1315 / 1321
页数:7
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