NITRIC-OXIDE - BIOLOGICAL MEDIATOR, MODULATOR AND EFFECTOR

被引:51
作者
RADOMSKI, MW [1 ]
机构
[1] UNIV ALBERTA,PERINATAL RES CTR,DEPT PHARMACOL,EDMONTON,AB,CANADA
关键词
NITRIC OXIDE; PHYSIOLOGY; PATHOLOGY;
D O I
10.3109/07853899509002585
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Nitric oxide (NO) is synthesized from L-arginine by at least three isoforms of NO synthase enzyme (NOS). Once generated NO can interact with a number of molecular targets including haem proteins, enzymes, DNA, thiols, oxygen and superoxide. These reactions determine the profile of NO as a major biological mediator, modulator and effector molecule.
引用
收藏
页码:321 / 329
页数:9
相关论文
empty
未找到相关数据