NITRIC-OXIDE - BIOLOGICAL MEDIATOR, MODULATOR AND EFFECTOR

被引：51

作者：

RADOMSKI, MW ^{[1
]}

机构：

[1] UNIV ALBERTA,PERINATAL RES CTR,DEPT PHARMACOL,EDMONTON,AB,CANADA

来源：

ANNALS OF MEDICINE | 1995年 / 27卷 / 03期

关键词：

NITRIC OXIDE; PHYSIOLOGY; PATHOLOGY;

D O I：

10.3109/07853899509002585

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nitric oxide (NO) is synthesized from L-arginine by at least three isoforms of NO synthase enzyme (NOS). Once generated NO can interact with a number of molecular targets including haem proteins, enzymes, DNA, thiols, oxygen and superoxide. These reactions determine the profile of NO as a major biological mediator, modulator and effector molecule.

引用

页码：321 / 329

页数：9