HISTOCHEMICAL STUDIES ON PAPILLARY HYPERPLASIA OF PALATE .I. METACHROMASIA MAST CELLS ACID MUCOPOLYSACCHARIDES AND GLYCOGEN

The present study demonstrates the increase in mast cells and glycogen in papillary hyperplasia over that seen in the normal palatal mucosa and suggests an increase in mast cells in premalignancy, assuming that papillary hyperplasia of the palate is accepted as a premalignant lesion. There were about twice as many mast cells in the papillary hyperplasia sections as in the normal sections. The increase in glycogen occurred in the epithelium at the base of the fissures. The distribution throughout the remaining epithelium was sparse. Mucopolysaccharide was concentrated in the submucous layer. © 1968.