LIPID-SUPPRESSED SINGLE-SECTION AND MULTISECTION PROTON SPECTROSCOPIC IMAGING OF THE HUMAN BRAIN

被引：86

作者：

SPIELMAN, DM

PAULY, JM

MACOVSKI, A

GLOVER, GH

ENZMANN, DR

机构：

[1] Departments of Radiology, Stanford University Medical Center, Stanford, California, 94305

[2] Electrical Engineering, Stanford University Medical Center, Stanford, California, 94305

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1992年 / 2卷 / 03期

关键词：

BRAIN; MR; FAT SUPPRESSION; IMAGE PROCESSING; MAGNETIC RESONANCE (MR); SPECTROSCOPY; METABOLITE MAPPING; PULSE SEQUENCES;

D O I：

10.1002/jmri.1880020302

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Spectroscopic images of the brain have great potential in disease diagnosis and treatment monitoring. Unfortunately, interfering lipid signals from subcutaneous fat and poor water suppression due to magnetic field inhomogeneities can make such images difficult to obtain. A pulse sequence that uses inversion recovery for lipid suppression and a spectral-spatial refocusing pulse for water suppression is introduced. In contrast to methods that eliminate fat signal by restricting the excited volume to lie completely within the brain, inversion-recovery techniques allow imaging of an entire section without such restrictions. In addition, the spectral-spatial pulse was designed to provide water suppression insensitive to a reasonable range of B0 and B1 inhomogeneities. Several data processing algorithms have also been developed and used in conjunction with the new pulse sequence to produce metabolite maps covering large volumes of the human brain. Images from single- and multisection studies demonstrate the performance of these techniques.

引用

页码：253 / 262

页数：10

共 32 条

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