NMR-STUDIES OF FLUORINATED VISUAL PIGMENT ANALOGS

被引：13

作者：

COLMENARES, LU

ASATO, AE

DENNY, M

MEAD, D

ZINGONI, JP

LIU, RSH

机构：

[1] Department of Chemistry, University of Hawaii, Honolulu, HI 96822

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 179卷 / 03期

关键词：

D O I：

10.1016/0006-291X(91)91720-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The 19F-nmr chemical shift data of isomeric pigments (11-cis and 9-cis) of four vinyl fluororhodopsins and two trifluororhodopsins have been recorded. When compared with model protonated Schiff bases, a set of F-nmr opsin shift parameter (FOS) was obtained. The data revealed regiospecific protein perturbations on the F-resonances. They can be interpreted in terms of specific protein interactions such as the postulated second point charge and other polar interactions as well as the common hydrophobic protein perturbation. © 1991.

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页码：1337 / 1343

页数：7

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