NUCLEIC-ACID BINDING-DRUGS .14. THE CRYSTAL-STRUCTURE OF 1-METHYL AMSACRINE HYDROCHLORIDE - RELATIONSHIPS TO DNA-BINDING ABILITY AND ANTITUMOR-ACTIVITY

被引：18

作者：

NEIDLE, S ^{[1
]}

WEBSTER, GD ^{[1
]}

BAGULEY, BC ^{[1
]}

DENNY, WA ^{[1
]}

机构：

[1] UNIV AUCKLAND, SCH MED, CANC RES LAB, AUCKLAND, NEW ZEALAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1986年 / 35卷 / 22期

关键词：

D O I：

10.1016/0006-2952(86)90004-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3915 / 3921

页数：7

共 31 条

[1] NUCLEIC-ACID BINDING-DRUGS .12. X-RAY CRYSTALLOGRAPHIC AND CONFORMATIONAL STUDIES ON THE ANTI-CANCER DRUG META-AMSA AND ITS MESYL DERIVATIVE [J].

ABRAHAM, ZHL ;

CUTBUSH, SD ;

KURODA, R ;

NEIDLE, S ;

ACHESON, RM ;

TAYLOR, GN .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1985, (03) :461-465

[2] POTENTIAL ANTITUMOR AGENTS .43. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF DIBASIC 9-AMINOACRIDINE-4-CARBOXAMIDES, A NEW CLASS OF ANTITUMOR AGENT [J].

ATWELL, GJ ;

CAIN, BF ;

BAGULEY, BC ;

FINLAY, GJ ;

DENNY, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (11) :1481-1485

[3] POTENTIAL ANTI-TUMOR AGENTS .35. QUANTITATIVE RELATIONSHIPS BETWEEN ANTI-TUMOR (L1210) POTENCY AND DNA-BINDING FOR 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE ANALOGS [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) :520-525

[4] ANTI-TUMOR ACTIVITY OF SUBSTITUTED 9-ANILINOACRIDINES - COMPARISON OF INVIVO AND INVITRO TESTING SYSTEMS [J].

BAGULEY, BC ;

NASH, R .

EUROPEAN JOURNAL OF CANCER, 1981, 17 (06) :671-679

[5] POTENTIAL ANTI-TUMOR AGENTS .34. QUANTITATIVE RELATIONSHIPS BETWEEN DNA-BINDING AND MOLECULAR-STRUCTURE FOR 9-ANILINOACRIDINES SUBSTITUTED IN THE ANILINO RING [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (02) :170-177

[6] STRUCTURE OF THE ANTITUMOUR AGENT M-AMSA (AMSACRINE), C21H19N3O3S, AS THE FREE BASE [J].

BUCKLETON, JS ;

WATERS, TN .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1984, 40 (SEP) :1587-1589

[7] POTENTIAL ANTI-TUMOR AGENTS .28. DEOXYRIBONUCLEIC-ACID POLYINTERCALATING AGENTS [J].

CAIN, BF ;

BAGULEY, BC ;

DENNY, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (07) :658-668

[8]

DAUTER Z, 1976, ROCZ CHEM, V50, P1573

[9]

Denny W.A., 1983, MOL ASPECTS ANTICANC, P1, DOI 10.1007/978-1-349-06010-8_1.

[10] POTENTIAL ANTI-TUMOR AGENTS .39. ANILINO RING GEOMETRY OF AMSACRINE AND DERIVATIVES - RELATIONSHIP TO DNA-BINDING AND ANTI-TUMOR ACTIVITY [J].

DENNY, WA ;

ATWELL, GJ ;

BAGULEY, BC .

JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (11) :1625-1630

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