FINE-NEEDLE ASPIRATION BIOPSY OF PEDIATRIC NEOPLASMS - CORRELATION BETWEEN ELECTRON-MICROSCOPY AND IMMUNOCYTOCHEMISTRY IN DIAGNOSIS AND CLASSIFICATION

被引:21
作者
AKHTAR, M
BEDROSSIAN, CWM
ALI, MA
BAKRY, M
机构
[1] Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh
[2] Department of Pathology, Iowa College of Medicine, Iowa City, Iowa
关键词
FNAB; BENIGN AND MALIGNANT NEOPLASMS; LYMPHOMA; SBRCT; PNET;
D O I
10.1002/dc.2840080314
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
A series of fine-needle aspiration biopsies performed in 635 children were reviewed. The diagnoses rendered in these patients included malignant lymphoma in 139 (21.9%); Hodgkin's disease, 25 (3.9%); neuroblastoma, 58 (9.1%); Wilms' Tumor, 37 (5.8%); Ewing's sarcoma, 32 (5.0%); rhabdomyosarcoma, 25 (3.9%); retinoblastoma, 22 (3.5%); leukemia infiltrate, 33 (5.2%); and miscellaneous tumors, 52 (8.2%). In 171 patients (269%), the biopsy was nondiagnostic. The cytomorphological characteristics of these lesions are briefly described and illustrated. Salient morphological features are further correlated with histological and ultrastructural appearances. Immunocytochemical patterns of these tumors are also discussed briefly.
引用
收藏
页码:258 / 265
页数:8
相关论文
共 28 条
[1]  
Tao LC, Pearson FG, Delarue NC, Et al., Percutaneous fine needle aspiration biopsy: Its value to clinical practice, Cancer, 45, pp. 1480-1485, (1980)
[2]  
Orell SA, Sterrett GF, Walter MN, Et al., Manual and atlas of fine needle aspiration cytology, (1986)
[3]  
Frable WJ, Fine needle aspiration biopsy
[4]  
A review, Hum Pathol, 14, 1, pp. 9-28, (1983)
[5]  
Koss LG
[6]  
Akhtar M, Ali MA, Sabbah R, Bakry M, Nash JE, Fine needle aspiration biopsy diagnosis of round cell malignant tumors of childhood: A combined light and electronmicroscopic approach, Cancer, 55, pp. 1805-1817, (1985)
[7]  
Wakely P, Thomas F, Kardos MD, Frable WJ, Application of fine needle aspiration biopsy to pediatrics, Hum Pathol, 19, pp. 1383-1386, (1988)
[8]  
Rajwanshi A, Rao KLN, Marwahs RK, Et al., Role of FNAC in childhood malignancies, Diagn Cytopathol, 5, pp. 378-382, (1989)
[9]  
Akhtar M, Ali MA, Huq M, Faulkner C, Fine needle aspiration biopsy: comparison of cellular yield with or without aspiration, Diagn Cytopathol, 5, pp. 162-165, (1989)
[10]  
Akhtar M, Bakry M, Nash EJ, An improved technique for processing aspiration biopsy for electron microscopy, Am J Clin Pathol, 85, pp. 57-60, (1986)