EFFECT OF SUBINHIBITORY CONCENTRATIONS OF CEFAMANDOLE AND CEFUROXIME ON ADHERENCE OF STAPHYLOCOCCUS-AUREUS AND STAPHYLOCOCCUS-EPIDERMIDIS TO POLYSTYRENE CULTURE PLATES
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作者:
CARSENTIETESSE, H
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
CARSENTIETESSE, H
DURANT, J
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
DURANT, J
BERNARD, E
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
BERNARD, E
MONDAIN, V
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
MONDAIN, V
ENTENZA, J
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
ENTENZA, J
DELLAMONICA, P
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机构:Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
DELLAMONICA, P
机构:
[1] Department of Infectious Diseases, Archet Hospital, Nice Cedex 3, 06202
The ability of cefamandole and cefuroxime to inhibit adherence of staphylococci to polystyrene culture plates was tested in an in vitro assay using eight strains each of Staphylococcus aureus and Staphylococcus epidermidis. The results indicated that subinhibitory concentrations of cefamandole and cefuroxime altered the adherence ability of both staphylococcal species, inhibition of adherence being more marked in the presence of cefamandole. It may be important to consider antiadherence properties in association with bactericidal activity when selecting agents for antibiotic prophylaxis.