ALUMINUM TOXICITY IN RAT HIPPOCAMPAL-NEURONS

被引：7

作者：

BRENNER, SR

YOON, KW

机构：

[1] ST LOUIS UNIV,CTR HLTH SCI,DIV NEUROSURG,ST LOUIS,MO 63110

[2] ST LOUIS UNIV,CTR HLTH SCI,DEPT NEUROL,ST LOUIS,MO 63110

[3] ST LOUIS UNIV,CTR HLTH SCI,DEPT PHARMACOL & PHYSIOL SCI,ST LOUIS,MO 63110

来源：

NEUROSCIENCE LETTERS | 1994年 / 178卷 / 02期

关键词：

ALUMINUM; NEURON; CELL DEATH; DEMENTIA;

D O I：

10.1016/0304-3940(94)90773-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A brief exposure of dissociated hippocampal culture to aluminum (AlCl3, 60 min) is toxic to neurons. The aluminum toxicity is independent of calcium or glutamate receptor activation. However, at a high concentration (1 mM), aluminum seems to have a protective effect.

引用

页码：260 / 262

页数：3

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