ALZHEIMERS-DISEASE - ISOPROTERENOL AND PROSTAGLANDIN-E1-STIMULATED CYCLIC-AMP ACCUMULATION IN LYMPHOCYTES

被引：29

作者：

EBSTEIN, RP

OPPENHEIM, G

STESSMAN, J

机构：

来源：

LIFE SCIENCES | 1984年 / 34卷 / 23期

关键词：

D O I：

10.1016/0024-3205(84)90211-X

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Reduced lymphocyte .beta.-adrenergic receptor activity was observed in patients with Alzheimer''s disease in aged controls; a parallel decline in lymphocytic prostaglandin E1 receptor activity was seen in the aged controls. In the Alzheimer patients, such lymphocytic prostaglandin E1 receptor activity was significantly raised and correlated with a rating scale for severity of dementia.

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页码：2239 / 2243

页数：5

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