PREPARATION OF A KEY INTERMEDIATE FOR THE SYNTHESIS OF THE (+/-)-PENTALENOLACTONE-E METHYL-ESTER BY CATALYTIC PALLADIUM-ENE CYCLIZATION/METHOXYCARBONYLATION

被引：42

作者：

OPPOLZER, W

XU, JZ

STONE, C

机构：

[1] Département de Chimie Organique, Université de Genève, Genève

来源：

HELVETICA CHIMICA ACTA | 1991年 / 74卷 / 03期

关键词：

D O I：

10.1002/hlca.19910740302

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bicyclic alcohol (+/-)-2, and advanced intermediate for the synthesis of the methyl ester 1 of pentalenolactone E, has been synthesized in nine operations starting from aldehyde 7. The key step 6 --> 9 is a Pd-catalyzed, tandem intramolecular alkyne allylation/carbonylation reaction.

引用

页码：465 / 468

页数：4

共 17 条

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