CARTILAGE TRANSFORMATION IN A COMPOSITE GRAFT OF DEMINERALIZED BOVINE BONE-MATRIX AND EAR PERICHONDRIUM USED IN A CHILD FOR THE RECONSTRUCTION OF THE NASAL-SEPTUM

被引：19

作者：

PIRSIG, W ^{[1
]}

BEAN, JK ^{[1
]}

LENDERS, H ^{[1
]}

VERWOERD, CDA ^{[1
]}

VERWOERDVERHOEF, HL ^{[1
]}

机构：

[1] ERASMUS UNIV ROTTERDAM,DEPT OTORHINOLARYNGOL,ROTTERDAM,NETHERLANDS

来源：

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 1995年 / 32卷 / 02期

关键词：

AURAL PINNA; SEPTAL PERFORATION; DEMINERALIZED BOVINE BONE MATRIX; CHONDRONEOGENESIS; COMPOSITE GRAFT;

D O I：

10.1016/0165-5876(94)01121-D

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

For the first time it was observed in a boy that a xenogenic implant of demineralized bovine bone matrix, enfolded in a pedicled flap of autogenic ear perichondrium, was transformed into autogenic cartilage. This new cartilage could be adequately used as a graft to bridge the cartilaginous defect of a nasal septum perforation. The defect was successfully closed by a technique employing four bipedicled mucosal advancement flaps of the septum and the nasal floor. The result of this pilot study, which is based on experiments in growing rabbits, appears to open the possibility to create de novo young and growing autogenic cartilage of substantial quantity in children, without the loss of the cartilage present.

引用

页码：171 / 181

页数：11

共 10 条

[1]

Bean, Verwoerd-Verhoef, Verwoerd, van der Heul, Chondroneogenesis in a collagen matrix, Fundamentals of Bone Growth, pp. 113-120, (1991)

[2]

Bean, Verwoerd-Verhoef, Meeuwis, Verwoerd, Reconstruction of the growing cricoid with a composite graft of demineralized bovine bone and autogenous perichondrium

[3]

a comparative study in rabbits, Int. J. Ped. Otorhinolaryngol., 25, pp. 163-172, (1993)

[4]

Bean, Verwoerd-Verhoef, Verwoerd, Reconstruction of the anterior laryngeal wall with a composite graft of demineralized bovine bone matrix and autogenous perichondrium, Otorhinolaryngology, 56, pp. 224-229, (1994)

[5]

Cottle, Loring, Fischer, Gaynon, The ‘maxilla-premaxilla’ approach to extensive nasal septum surgery, Arch. Otolaryngol., 68, pp. 301-313, (1958)

[6]

Fairbanks, Closure of nasal septal perforations, Arch. Otolaryngol., 106, pp. 509-513, (1980)

[7]

Lenders, Pirsig, Diagnostic value of acoustic rhinometry: patients with allergic and vasomotor rhinitis compared with normal controls, Rhinology, 28, pp. 5-16, (1990)

[8]

Pirsig, Growth of the deviated septum and its influence on midfacial development, Facial. Plast. Surg., 8, pp. 224-232, (1992)

[9]

Prescott, Laing, Medium term fate of cartilage grafts from children after laryngo-tracheoplasty, Int. J. Ped. Otorhinolaryngol., 27, pp. 163-171, (1993)

[10]

Schultz-Coulon, Experiences with the bridge-flap technique for the repair of large nasal septal perforations, Rhinology, 32, pp. 25-33, (1994)

← 1 →